Alerts

What is it? Medetomidine is a non-opioid sedative used as a veterinary drug.It is very potent — consuming even a small amount can result in heavy sedation. The sample was acquired in Victoria in the last week. Important to note: Medetomidine is NOT an opioid — its effects will not be reversed by naloxone. If purchasing bromazolam avoid use with Read More The post Medetomidine found in crystal / powder expected to contain bromazolam first appeared on The Know.

​Ketamine analogues copy ketamine’s chemical makeup but can produce different effects, including stronger dissociation or hallucinatory episodes. Recent detections in NSW include: 2′-fluoro-2-oxo-PCE in white powder and crystal that was expected to be ketamine only, or amphetamine. 2-oxo-PCE in a white powder that was expected to be ketamine only. Know the risks Effects to look out for If you or others experience these symptoms, Read More The post Ketamine analogues recently detected in NSW first appeared on The Know.

​Tablet appearance is not a reliable indicator of drug contents. Dose is reported as MDMA free base. Multiple ‘Philipp Plein’ detections in varying colours, weights, purity and dose, some at least 138 mg MDMA. Multiple capsules of various appearances with >150 mg MDMA found. Know the risks Effects to look out for If you or others experience these symptoms after Read More The post Multiple high dose MDMA (ecstasy) tablets and capsules circulating in NSW first appeared on The Know.

A grey ‘Maserati’ press pill was brought to CanTEST for testing, expected to contain MDMA. The sample was found to have a mass of 430mg with 45% purity (194mg free base). What does this mean? A common dose of MDMA is between 80-120mg. This means the amount of MDMA in this pill is significantly more than the amount a person Read More The post High Dose MDMA Pill first appeared on The Know.

What is Tiletamine? Tiletamine is a ketamine analogue that is much more potent and longer lasting (up to 4-6hrs) than ketamine. As an anaesthetic, tiletamine has the potential to cause loss of coordination, motor control, or consciousness at high doses. The effects of taking tiletamine will not match those of 4-MMC. What is N-Benzylcyclohexanamine? N-Benzylcyclohexanamine is a chemical used as Read More The post Tiletamine and N-Benzylcyclohexanamine missold as ‘M-CAT’ or 4-MMC first appeared on The Know.

A capsule filled with off-white powder expected to contain an unknown opioid was found to contain Rilmazafone. Rilmazafone is a benzodiazepine prodrug, meaning the body converts the substance into a benzo after consumption (rilmazolam). Because of the conversion time in the body, the onset of effects can be delayed and may take 2-3 hours or more. Rilmazafone is not readily Read More The post Rilmalzafone found in ‘opioid’ capsule first appeared on The Know.

A BAGGIE FILLED WITH WHITE POWDER was brought to CanTEST for testing. The expectations for its contents were unknown by the service user. Testing at CanTEST confirmed the substance is 5-hydroxytryptophan (5-HTP). 5-HTP is available in some other jurisdictions without a prescription (like NZ, UK, EU and USA), however it isn’t on the TGA’s Permissible Ingredients list in Australia. Effects Read More The post 5-Hydroxytryptophan found in unknown powder first appeared on The Know.

5-cyano-isotodesnitazene (isotocyanozene) has recently been found in toxicology and powder samples, in South-East Queensland. There is limited potency or toxicity data available on 5-cyano-isotodesnitazene globally as it a novel nitazene only recently detected for the first time in Australia. Nitazenes are very strong synthetic opioids that work like heroin or fentanyl and could produce life-threatening toxicity in small amounts. The Read More The post First report of 5-cyano isotodesnitazene in Queensland first appeared on The Know.

[Issued 7 October 2025, updated 8 October 2025] Tablet appearance is not a reliable indicator of drug contents. Dose is reported as MDMA free base. Multiple tablets of various appearances with >150mg MDMA (free base) found. K​n​​ow the risks Effects to look out for If you or others experience these symptoms after taking MDMA, get help immediately. Getting help If you or Read More The post Updated 08/10/25: Multiple high dose MDMA (ecstasy) tablets and capsules circulating in NSW first appeared on The Know.

There has been a recent case of N-pyrrolidino protonitazene (also known as protonitazepyne) and protonitazene detected in toxicology and tablet samples, in South-East Queensland. N-pyrrolidino protonitazene and protonitazene are very strong synthetic opioids that work like heroin or fentanyl and can produce life-threatening toxicity in small amounts. The appearance of the sample is a pale yellow, bear shaped pressed pill Read More The post Confirmed detection of N-pyrrolidino protonitazene and protonitazene in Queensland first appeared on The Know.